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By Hannah Bachmeier, 2026
Hannah Bachmeier is an Associate Scientist at Aralez Bio who works to engineer proteins to optimize our biocatalysis pathways to make the production of noncanonical amino acids greener.
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"The full potential of advanced peptide drug design relies heavily on the accessibility of high-quality noncanonical amino acids (ncAAs). However, as global demand for these specialized building blocks accelerates, the environmental toll of traditional, fossil-fueled chemical manufacturing threatens to compromise the industry’s sustainability goals.
Biocatalysis bridges this gap by replacing resource-heavy chemical paths with a streamlined, single-step enzymatic synthesis. By operating at ambient pressure and using water as a primary solvent, this green alternative minimizes greenhouse gas emissions and waste by 99%, ensuring the future of medicine is as sustainable as it is effective."
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Read the full whitepaper to explore the integration of green chemistry principles into peptide manufacturing—and how Aralez Bio is optimizing process mass intensity (PMI) to build a cleaner future for drug discovery.
Download the full whitepaper: Biocatalysis as a Green Alternative to Amino Acid Synthesis (PDF).
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