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The first enzyme platform purpose-built for diverse, scalable ncAA synthesis. A process that is elegant, green, and unlocks chemical diversity.
01Science
Discover the innovative science behind our game-changing ncAAs.
01Enzyme Engineering
Through directed evolution, we create specific enzymes for noncanonical amino acid synthesis. Our focus is on both breadth and practicality: enzymes that open access to wide chemical diversity while remaining highly active. This platform makes ncAAs not just possible to imagine, but also practical to produce.
02Biocatalysis
Our engineered enzymes perform biocatalysis at high concentrations in water, minimizing use of solvents and hazardous materials, and optimizing process mass intensity. These reactions routinely reach >90% yields within hours, providing an efficient, sustainable route to noncanonical amino acids at manufacturing scale.
03 Downstream Processing
After biocatalysis, ncAAs are isolated by filtration or recrystallization—no chromatography required. Subsequent derivatization yields protected variants, including Fmoc and Boc.
01Enzyme Engineering
Through directed evolution, we create specific enzymes for noncanonical amino acid synthesis. Our focus is on both breadth and practicality: enzymes that open access to wide chemical diversity while remaining highly active. This platform makes ncAAs not just possible to imagine, but also practical to produce.
02Biocatalysis
Our engineered enzymes perform biocatalysis at high concentrations in water, minimizing use of solvents and hazardous materials, and optimizing process mass intensity. These reactions routinely reach >90% yields within hours, providing an efficient, sustainable route to noncanonical amino acids at manufacturing scale
03 Downstream Processing
After biocatalysis, ncAAs are isolated by filtration or recrystallization—no chromatography required. Subsequent derivatization yields protected variants, including Fmoc and Boc.
Through directed evolution, we create specific enzymes for noncanonical amino acid synthesis. Our focus is on both breadth and practicality: enzymes that open access to wide chemical diversity while remaining highly active. This platform makes ncAAs not just possible to imagine, but also practical to produce.
Our engineered enzymes perform biocatalysis at high concentrations in water, minimizing use of solvents and hazardous materials, and optimizing process mass intensity. These reactions routinely reach >90% yields within hours, providing an efficient, sustainable route to noncanonical amino acids at manufacturing scale.
After biocatalysis, ncAAs are isolated by filtration or recrystallization—no chromatography required. Subsequent derivatization yields protected variants, including Fmoc and Boc.
02Quality
High-purity building blocks, traceable supply chain, and experienced QA/QC support that’s designed to meet the demands of pharmaceutical manufacturing.
A Qualified Supply Partner
ISO 9001:2015 certified since 2022 by DEKRA
Product documentation and traceability, including certificate of analysis and analytics
U.S.-based, sustainable manufacturing for reliable delivery at scale
Qualified supplier with major API manufacturers
Manufacturing at all Scales
USP <1504> compliant starting materials for therapeutics
>95% purity for drug discovery and pre-clinical applications
>99% purity with <0.1% of any single impurity, >99% ee, TSE/BSE free for clinical and commercial batches
Batch sizes up to 100 kilograms, supporting scale up and process validation
Experienced Quality Team
ISO 9001, quality assurance, and quality control for pharmaceutical products.
Analytical chemistry experience in method development and release testing
Through directed evolution, we create specific enzymes for noncanonical amino acid synthesis. Our focus is on both breadth and practicality: enzymes that open access to wide chemical diversity while remaining highly active. This platform makes ncAAs not just possible to imagine, but also practical to produce.
Through directed evolution, we create specific enzymes for noncanonical amino acid synthesis. Our focus is on both breadth and practicality: enzymes that open access to wide chemical diversity while remaining highly active. This platform makes ncAAs not just possible to imagine, but also practical to produce.
After biocatalysis, ncAAs are isolated by filtration or recrystallization—no chromatography required. Subsequent derivatization yields protected variants, including Fmoc and Boc.
Through directed evolution, we create specific enzymes for noncanonical amino acid synthesis. Our focus is on both breadth and practicality: enzymes that open access to wide chemical diversity while remaining highly active. This platform makes ncAAs not just possible to imagine, but also practical to produce.
Through directed evolution, we create specific enzymes for noncanonical amino acid synthesis. Our focus is on both breadth and practicality: enzymes that open access to wide chemical diversity while remaining highly active. This platform makes ncAAs not just possible to imagine, but also practical to produce.
After biocatalysis, ncAAs are isolated by filtration or recrystallization—no chromatography required. Subsequent derivatization yields protected variants, including Fmoc and Boc.
Certified, documented, and trusted by leading API manufacturers to deliver consistency at scale.
We deliver the quality you need, from early discovery through commercial development.
Decades of pharmaceutical QA/QC and analytical chemistry expertise to safeguard every batch.
03Sustainability
Our enzyme platform is best-in-class, outperforming traditional manufacturing approaches by 10–100x across energy, waste, and carbon emissions.
Sustainable Process
Parameters for each method to make 100 kilograms of ncAA.
kilograms of ncAA.
Sustainable Byproducts
Biocatalysis significantly reduces waste, energy, and emissions when compared to traditional ncAA manufacturing approaches.
less waste
less waste
less waste
emissions when compared to traditional ncAA
manufacturing approaches.
less waste
less waste
less CO2
