From drug discovery to manufacturing, seamlessly unlock diverse noncanonical amino acids at any scale.

01Discovery

Unmatched Choice

Power discovery with the world’s largest and most unique ncAA portfolio — 70% of which is exclusive to us.

Our platform extends ncAA design space beyond the limits of canonical residues and conventional chemical synthesis, unlocking properties essential for next-generation therapeutics.

1Modify backbone to resist proteolytic degradation.
2 Tune binding interactions or introduce reactive handles.
3 Add rigidifying groups to mask polar backbone and improve membrane permeability.
4Incorporate polar or charged groups to reduce lipophilicity.
5 Use N-methylation to boost passive permeability and oral bioavailability.
6Reduce hydrophobicity to cut hemolytic toxicity.

Breakthrough Speed

Thanks to our enzymatic methods, we deliver ncAAs rapidly and at scale — accelerating your research timelines like never before.

Seamless Compatibility

Our ncAAs integrate seamlessly — expanding chemical space, boosting hit quality, and unlocking novel therapeutic targets across the entire discovery workflow.

Precision Library Design

Incorporate stability, potency, permeability, and other drug-like properties into your peptide libraries from day one.

In Silico Ready

Bridge the gap from computational hits to lab-ready building blocks with on-demand ncAAs.

Display Platform Friendly

Drop our ncAAs into mRNA and phage display platforms to broaden diversity and discover novel scaffolds.

Precision Library Design

Incorporate stability, potency, permeability, and other drug-like properties into your peptide libraries from day one.

In Silico Ready

Bridge the gap from computational hits to lab-ready building blocks with on-demand ncAAs.

Display Platform Friendly

Drop our ncAAs into mRNA and phage display platforms to broaden diversity and discover novel scaffolds.

Accelerated Lead Optimization

Once a hit is identified, tune selectivity, stability,
and pharmacokinetics with precision.

Shop our product portfolio

With the world’s largest collection of ncAAs, 70% of which are exclusive to us, you’re bound to unlock diverse choices.

02Manufacturing & CMC

Helping you source the right noncanonical amino acids—at the right scale, quality, and price—for every stage of development. Our U.S.-based manufacturing, biocatalytic platform, and deep expertise in amino acid chemistry give you the control, continuity, and confidence to move from discovery to commercial without surprises.

Scale Without Surprises

Our enzyme-driven methods scale seamlessly from milligram to kilogram to metric ton capacity — avoiding costly tech transfers or redesigns.

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Green Chemistry, Real Impact

Our biocatalytic platform slashes Scope 1 & 2 emissions, energy use, and process mass intensity (PMI) — while domestic production reduces Scope 3 emissions.

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Dependability Built In

Reliable, on-spec delivery at every stage, backed by ISO 9001 certification, and proven at our California manufacturing site.

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High Value Without High Costs

Biocatalysis reduces steps, waste, and raw material costs, keeping your programs moving without overspending.

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Engineered for Every Workflow

We supply ncAAs compatible with solid-phase, liquid-phase, recombinant, and fragment-based synthesis — customized for your protecting groups, purity, and scale.

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Talk to our team

Whether you’re looking to manufacture up to metric ton capacity or seeking quality documentation, we’re here to help.

03Other Industries

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Product Name
Product ID
11785
CAS
321455-12-9
Purity
<97%
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